E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells

RATIONALE: The majority of current cardiovascular cell-therapy trials use bone marrow progenitor cells (BM PCs) and achieve only modest efficacy; the limited potential of these cells to differentiate into endothelial-lineage cells is one of the major barriers to the success of this promising therapy...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Xu, Shiyue, Tao, Jun, Yang, Liu, Zhang, Eric, Boriboun, Chan, Zhou, Junlan, Sun, Tianjiao, Cheng, Min, Huang, Kai, Shi, Jiawei, Dong, Nian-Guo, Liu, Qinghua, Zhao, Ting C, Qiu, Hongyu, Harris, Robert A, Chandel, Navdeep S, Losordo, Douglas W., Qin, Gangjian
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021021/
https://ncbi.nlm.nih.gov/pubmed/29358228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.311814
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