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1,3- and 1,4-Benzdiyne equivalents for regioselective synthesis of polycyclic heterocycles

We have devised a novel 1,3-benzdiyne equivalent, capable of quadruple functionalization by sequential benzyne generation and reaction with arynophiles. The key features of this method include the chemoselective generation of two triple bonds in a single benzene ring under fluoride-mediated mild con...

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Vydáno v:Chem Sci
Hlavní autoři: Ikawa, Takashi, Masuda, Shigeaki, Takagi, Akira, Akai, Shuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020534/
https://ncbi.nlm.nih.gov/pubmed/30155171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00798h
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