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Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection

Emergency granulopoiesis is a hematopoietic program of stem cell-driven neutrophil production used to counteract immune cell exhaustion following infection. Shigella flexneri is a Gram-negative enteroinvasive pathogen controlled by neutrophils. In this study, we use a Shigella-zebrafish (Danio rerio...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Willis, Alexandra R., Torraca, Vincenzo, Gomes, Margarida C., Shelley, Jennifer, Mazon-Moya, Maria, Filloux, Alain, Lo Celso, Cristina, Mostowy, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020294/
https://ncbi.nlm.nih.gov/pubmed/29946048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00933-18
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