Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA)

BACKGROUND: Circulating tumor DNA (ctDNA) and miRNA (ctmiRNA) are promising biomarkers for early tumor diagnosis, prognosis and monitoring, and to predict therapeutic response. However, a clear understanding of the fine control on their circulating levels is still lacking. METHODS: Three human color...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Gasparello, Jessica, Allegretti, Matteo, Tremante, Elisa, Fabbri, Enrica, Amoreo, Carla Azzurra, Romania, Paolo, Melucci, Elisa, Messana, Katia, Borgatti, Monica, Giacomini, Patrizio, Gambari, Roberto, Finotti, Alessia
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020232/
https://ncbi.nlm.nih.gov/pubmed/29941002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0788-1
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