A pyruvate carbon flux tugging strategy for increasing 2,3-butanediol production and reducing ethanol subgeneration in the yeast Saccharomyces cerevisiae

BACKGROUND: The yeast Saccharomyces cerevisiae is a promising host cell for producing a wide range of chemicals. However, attempts to metabolically engineer Crabtree-positive S. cerevisiae invariably face a common issue: how to reduce dominant ethanol production. Here, we propose a yeast metabolic e...

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Detalhes bibliográficos
Publicado no:Biotechnol Biofuels
Main Authors: Ishii, Jun, Morita, Keisuke, Ida, Kengo, Kato, Hiroko, Kinoshita, Shohei, Hataya, Shoko, Shimizu, Hiroshi, Kondo, Akihiko, Matsuda, Fumio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020211/
https://ncbi.nlm.nih.gov/pubmed/29983743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-018-1176-y
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