Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines

All-trans retinoic acid (ATRA) up-regulates, in laboratory animals, the expression of the gut homing markers α4β7 integrin and CCR9 on lymphocytes, increasing their gut tropism. Here, we show that, in healthy adult volunteers, ATRA induced an increase of these gut homing markers on T cells in vivo i...

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Publicat a:Vaccine
Autors principals: Mwanza-Lisulo, Mpala, Chomba, Mumba S., Chama, Mubanga, Besa, Ellen C., Funjika, Evelyn, Zyambo, Kanekwa, Banda, Rose, Imikendu, Mercy, Sianongo, Sandie, Hancock, Robert E.W., Lee, Amy, Chilengi, Roma, Stagg, Andy J., Namangala, Boniface, Kelly, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020133/
https://ncbi.nlm.nih.gov/pubmed/29801999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.04.083
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