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Single degranulations in Natural Killer cells can mediate target cell killing

Natural killer (NK) cells are cytotoxic lymphocytes important in defense against viral infection and cancer. NK cells mediate cytotoxicity predominantly through directed secretion of lytic granules which are specialized lysosome-related organelles, containing effector molecules such as perforin and...

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Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Gwalani, Lavesh A., Orange, Jordan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020067/
https://ncbi.nlm.nih.gov/pubmed/29592963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701500
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