Altering the GTP binding site of the DNA/RNA-binding protein, Translin/TB-RBP, decreases RNA binding and may create a dominant negative phenotype

The DNA/RNA-binding protein, Translin/Testis Brain RNA-binding protein (Translin/TB-RBP), contains a putative GTP binding site in its C-terminus which is highly conserved. To determine if guanine nucleotide binding to this site functionally alters nucleic acid binding, electrophoretic mobility shift...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Chennathukuzhi, Vargheese M., Kurihara, Yasuyuki, Bray, Jeffrey D., Yang, Juxiang, Hecht, Norman B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.21.4433
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