Rapid loss of early antigen-presenting activity of lymph node dendritic cells against Ag85A protein following Mycobacterium bovis BCG infection

BACKGROUND: Control of Mycobacterium tuberculosis (Mtb) infection requires CD4(+) T-cell responses and major histocompatibility complex class II (MHC II) presentation of Mtb antigens (Ags). Dendritic cells (DCs) are the most potent of the Ag-presenting cells and are central to the initiation of T-ce...

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Veröffentlicht in:BMC Immunol
Hauptverfasser: Xu, Zhengzhong, Xia, Aihong, Li, Xin, Zhu, Zhaocheng, Shen, Yechi, Jin, Shanshan, Lan, Tian, Xie, Yuqing, Wu, Han, Meng, Chuang, Sun, Lin, Yin, Yuelan, Chen, Xiang, Jiao, Xinan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019797/
https://ncbi.nlm.nih.gov/pubmed/29940854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-018-0258-8
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