A CD8α(−) Subset of CD4(+)SLAMF7(+) Cytotoxic T Cells is Expanded in Patients with IgG4-Related Disease and Decreases following Glucocorticoid Treatment

OBJECTIVE: An unconventional population of CD4(+)SLAMF7(+) cytotoxic T(EM) cells (CD4(+)CTLs) has been linked causally to IgG4-related disease (IgG4-RD). Glucocorticoids represent the first line therapeutic approach in patients with IgG4-RD but their mechanism of action in this specific condition re...

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Publicado en:Arthritis Rheumatol
Autores principales: Della-Torre, Emanuel, Bozzalla-Cassione, Emanuele, Sciorati, Clara, Ruggiero, Eliana, Lanzillotta, Marco, Bonfiglio, Silvia, Mattoo, Hamid, Perugino, Cory A., Bozzolo, Enrica, Rovati, Lucrezia, Arcidiacono, Paolo Giorgio, Balzano, Gianpaolo, Lazarevic, Dejan, Bonini, Chiara, Falconi, Massimo, Stone, John H., Dagna, Lorenzo, Pillai, Shiv, Manfredi, Angelo A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019645/
https://ncbi.nlm.nih.gov/pubmed/29499100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40469
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