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Statins: pros and cons

Statins inhibit the critical step of cholesterol synthesis in which 3-hydroxy-3-methylglutaryl coenzyme A (HMGC) is transformed to mevalonate by the enzyme HMGC reductase. By doing so, they have a potent lipid-lowering effect that reduces cardiovascular risk and decreases mortality. Since the mevalo...

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Detalhes bibliográficos
Publicado no:Med Clin (Barc)
Main Authors: Pinal-Fernandez, Iago, Casal-Dominguez, Maria, Mammen, Andrew L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019636/
https://ncbi.nlm.nih.gov/pubmed/29292104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.medcli.2017.11.030
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