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Inhibition of miR-141-3p ameliorates the negative effects of post-stroke social isolation in aged mice

BACKGROUND AND PURPOSE: Social isolation increases mortality and impairs recovery after stroke in clinical populations. These detrimental effects have been recapitulated in animal models, although the exact mechanism mediating these effects remains unclear. Dysregulation of microRNAs (miRNAs) occurs...

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Publicado en:Stroke
Main Authors: Verma, Rajkumar, Ritzel, Rodney M., Harris, Nia M, Lee, Juneyoung, Kim, TaeHee, Pandi, Gopal, Vemuganti, Raghu, McCullough, Louise D
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019570/
https://ncbi.nlm.nih.gov/pubmed/29866755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.118.020627
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