Phase IIb trial of an alpha-7 nicotinic receptor partial agonist with and without nicotine patch for withdrawal-associated cognitive deficits and tobacco abstinence

PURPOSE/BACKGROUND: The objective of this study was to determine whether a novel alpha-7 nicotinic acetylcholine receptor (nAChR) partial agonist improves cognition during nicotine withdrawal and improves abstinence rates. To do so, the effect of the alpha-7 nAChR partial agonist, encenicline, on co...

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Publicat a:J Clin Psychopharmacol
Autors principals: Schuster, Randi Melissa, Pachas, Gladys N, Stoeckel, Luke, Cather, Corinne, Nadal, Mireya, Mischoulon, David, Schoenfeld, David A., Zhang, Haiyue, Ulysse, Christine, Dodds, Elisabeth B., Sobolewski, Sara, Hudziak, Vicenta, Hanly, Ailish, Fava, Maurizio, Evins, A. Eden
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019566/
https://ncbi.nlm.nih.gov/pubmed/29912798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JCP.0000000000000919
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