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The Apolipoprotein E Mimetic Peptide AEM-2 Attenuates Mitochondrial Injury And Apoptosis In Human THP-1 Macrophages

Cardiovascular disease, specifically atherosclerosis, is exacerbated by hypercholesterolemia. Current therapies that target lipid lowering, however, are not effective in all patients. Apolipoprotein E (apoE) plays an important role in mediating the clearance of plasma cholesterol and also exerts num...

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Bibliografiske detaljer
Udgivet i:Curr Top Pept Protein Res
Main Authors: Giordano-Mooga, Samantha, Datta, Geeta, Wolkowicz, Paul, Garber, David W., Palgunachari, Mayakonda, White, C. Roger, Anantharamaiah, G.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019287/
https://ncbi.nlm.nih.gov/pubmed/29955206
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