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Up-regulation of cholesterol 24-hydroxylase following hypoxia-ischemia in neonatal mouse brain
BACKGROUND: Maintenance of cholesterol homeostasis is crucial for brain development. Brain cholesterol relies on de novo synthesis and is cleared primarily by conversion to 24S-hydroxycholesterol (24S-HC) with brain-specific cholesterol 24-hydroxylase (CYP46A1). We aimed to investigate the impact of...
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| Publicado no: | Pediatr Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6019156/ https://ncbi.nlm.nih.gov/pubmed/29718007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2018.49 |
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