Single-dose oral ciprofloxacin prophylaxis as a response to a meningococcal meningitis epidemic in the African meningitis belt: A 3-arm, open-label, cluster-randomized trial

BACKGROUND: Antibiotic prophylaxis for contacts of meningitis cases is not recommended during outbreaks in the African meningitis belt. We assessed the effectiveness of single-dose oral ciprofloxacin administered to household contacts and in village-wide distributions on the overall attack rate (AR)...

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Pubblicato in:PLoS Med
Autori principali: Coldiron, Matthew E., Assao, Bachir, Page, Anne-Laure, Hitchings, Matt D. T., Alcoba, Gabriel, Ciglenecki, Iza, Langendorf, Céline, Mambula, Christopher, Adehossi, Eric, Sidikou, Fati, Tassiou, Elhadji Ibrahim, De Lastours, Victoire, Grais, Rebecca F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019097/
https://ncbi.nlm.nih.gov/pubmed/29944651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002593
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