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Characterization of Covalent-Reversible EGFR Inhibitors

[Image: see text] Within the spectrum of kinase inhibitors, covalent-reversible inhibitors (CRIs) provide a valuable alternative approach to classical covalent inhibitors. This special class of inhibitors can be optimized for an extended drug-target residence time. For CRIs, it was shown that the fa...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Smith, Steven, Keul, Marina, Engel, Julian, Basu, Debjit, Eppmann, Simone, Rauh, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018958/
https://ncbi.nlm.nih.gov/pubmed/29963651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00157
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