Prospective Discrimination of Controllers From Progressors Early After Low-Dose Mycobacterium tuberculosis Infection of Cynomolgus Macaques using Blood RNA Signatures

The cynomolgus macaque model of low-dose Mycobacterium tuberculosis infection recapitulates clinical aspects of human tuberculosis pathology, but it is unknown whether the 2 systems are sufficiently similar that host-based signatures of tuberculosis will be predictive across species. By blind predic...

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Veröffentlicht in:J Infect Dis
Hauptverfasser: Thompson, Ethan G, Shankar, Smitha, Gideon, Hannah P, Braun, Jackie, Valvo, Joe, Skinner, Jason A, Aderem, Alan, Flynn, JoAnne L, Lin, Philana Ling, Zak, Daniel E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018950/
https://ncbi.nlm.nih.gov/pubmed/29325117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy006
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