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2-carba cyclic phosphatidic acid suppresses inflammation via regulation of microglial polarisation in the stab-wounded mouse cerebral cortex

Traumatic brain injury (TBI) is caused by physical damage to the brain and it induces blood-brain barrier (BBB) breakdown and inflammation. To diminish the sequelae of TBI, it is important to decrease haemorrhage and alleviate inflammation. In this study, we aimed to determine the effects of 2-carba...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Hashimoto, Kei, Nakashima, Mari, Hamano, Ayana, Gotoh, Mari, Ikeshima-Kataoka, Hiroko, Murakami-Murofushi, Kimiko, Miyamoto, Yasunori
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018705/
https://ncbi.nlm.nih.gov/pubmed/29946114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27990-1
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