Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography

Inflammation plays an important role in the development of atherosclerosis and its complications. Because the folate receptor β (FR-β) is selectively expressed on macrophages, an FR targeted imaging agent could be useful for assessment of atherosclerotic inflammation. We investigated aluminum fluori...

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Pubblicato in:Sci Rep
Autori principali: Silvola, Johanna M. U., Li, Xiang-Guo, Virta, Jenni, Marjamäki, Päivi, Liljenbäck, Heidi, Hytönen, Jarkko P., Tarkia, Miikka, Saunavaara, Virva, Hurme, Saija, Palani, Senthil, Hakovirta, Harri, Ylä-Herttuala, Seppo, Saukko, Pekka, Chen, Qingshou, Low, Philip S., Knuuti, Juhani, Saraste, Antti, Roivainen, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018703/
https://ncbi.nlm.nih.gov/pubmed/29946129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27618-4
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