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C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway

The mechanisms that connect complement system activation and basal deposit formation in early stages of age-related macular degeneration (AMD) are insufficiently understood, which complicates the design of efficient therapies to prevent disease progression. Using human fetal (hf) retinal pigment epi...

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Publicat a:Sci Rep
Autors principals: Fernandez-Godino, Rosario, Pierce, Eric A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018664/
https://ncbi.nlm.nih.gov/pubmed/29946065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28143-0
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