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C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway
The mechanisms that connect complement system activation and basal deposit formation in early stages of age-related macular degeneration (AMD) are insufficiently understood, which complicates the design of efficient therapies to prevent disease progression. Using human fetal (hf) retinal pigment epi...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6018664/ https://ncbi.nlm.nih.gov/pubmed/29946065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28143-0 |
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