Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E

Translation of mRNA into protein has a fundamental role in neurodevelopment, plasticity, and memory formation; however, its contribution in the pathophysiology of depressive disorders is not fully understood. We investigated the involvement of MNK1/2 (MAPK-interacting serine/threonine-protein kinase...

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Udgivet i:Nat Commun
Main Authors: Aguilar-Valles, Argel, Haji, Nabila, De Gregorio, Danilo, Matta-Camacho, Edna, Eslamizade, Mohammad J., Popic, Jelena, Sharma, Vijendra, Cao, Ruifeng, Rummel, Christoph, Tanti, Arnaud, Wiebe, Shane, Nuñez, Nicolas, Comai, Stefano, Nadon, Robert, Luheshi, Giamal, Mechawar, Naguib, Turecki, Gustavo, Lacaille, Jean-Claude, Gobbi, Gabriella, Sonenberg, Nahum
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018502/
https://ncbi.nlm.nih.gov/pubmed/29941989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04883-5
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