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Inhibition of Inflammation, Suppression of Matrix Metalloproteinases, Induction of Neurogenesis, and Antioxidant Property Make Bryostatin-1 a Therapeutic Choice for Multiple Sclerosis

Multiple sclerosis (MS) is a neurodegenerative disease characterized by inflammation and myelin damage. Pro-inflammatory cytokines, oxidative stress, high level of matrix metalloproteinases (MMPs) activity and blood–brain barrier (BBB) damage, immune-mediated destruction of myelin and neuron loss ar...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Safaeinejad, Fahimeh, Bahrami, Soheyl, Redl, Heinz, Niknejad, Hassan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018466/
https://ncbi.nlm.nih.gov/pubmed/29971003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00625
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