Glycosphingolipids Prevent APAP and HMG-CoA Reductase Inhibitors-mediated Liver Damage: A Novel Method for “Safer Drug” Formulation that Prevents Drug-induced Liver Injury

Background and Aims: Acetaminophen (APAP) and HMG-CoA reductase inhibitors are common causes of drug-induced liver injury (DILI). This study aimed to determine the ability to reduce APAP- and statins-mediated liver injury by using formulations that combine glycosphingolipids and vitamin E. Methods:...

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Detalhes bibliográficos
Publicado no:J Clin Transl Hepatol
Main Authors: Mizrahi, Meir, Adar, Tomer, Lalazar, Gadi, Nachman, Dean, El Haj, Madi, Ben Ya’acov, Ami, Lichtenstein, Yoav, Shabat, Yehudit, Kanovich, Dimitri, Zolotarov, Lida, Ilan, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: XIA & HE Publishing Inc. 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018318/
https://ncbi.nlm.nih.gov/pubmed/29951356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14218/JCTH.2017.00071
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