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Stimulation of the Internal Ribosome Entry Site (IRES)-Dependent Translation of Enterovirus 71 by DDX3X RNA Helicase and Viral 2A and 3C Proteases

The translation of enterovirus 71 (EV71) is mediated by an internal ribosome entry site (IRES)-dependent manner. EV71 IRES comprises five highly structured domains (domains II-VI) in the 5′-untranslated region of the viral mRNA. A conserved AUG triplet residing in domain VI is proposed to be the rib...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Su, Yu-Siang, Tsai, Ai-Hsuan, Ho, Yueh-Feng, Huang, Shin-Yi, Liu, Yen-Chun, Hwang, Lih-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018165/
https://ncbi.nlm.nih.gov/pubmed/29971060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01324
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