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PER, a Circadian Clock Component, Mediates the Suppression of MMP-1 Expression in HaCaT Keratinocytes by cAMP

Skin circadian clock system responds to daily changes, thereby regulating skin functions. Exposure of the skin to UV irradiation induces the expression of matrix metalloproteinase-1 (MMP-1) and causes DNA damage. It has been reported both DNA repair and DNA replication are regulated by the circadian...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yeom, Miji, Lee, HansongI, Shin, Seoungwoo, Park, Deokhoon, Jung, Eunsun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017963/
https://ncbi.nlm.nih.gov/pubmed/29570674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040745
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