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Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions

Protein–protein interactions (PPIs) are tremendously important for the function of many biological processes. However, because of the structure of many protein–protein interfaces (flat, featureless and relatively large), they have largely been overlooked as potential drug targets. In this review, we...

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Pubblicato in:Molecules
Autori principali: Robertson, Naomi S., Spring, David R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017787/
https://ncbi.nlm.nih.gov/pubmed/29671834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040959
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