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High Level Expression and Purification of the Clinically Active Antimicrobial Peptide P-113 in Escherichia coli
P-113, which was originally derived from the human saliva protein histatin 5, is a histidine-rich antimicrobial peptide with the sequence AKRHHGYKRKFH. P-113 is currently undergoing phase II clinical trial as a pharmaceutical agent to fight against fungal infections in HIV patients with oral candidi...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6017664/ https://ncbi.nlm.nih.gov/pubmed/29601518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040800 |
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