In Vitro Inhibitory Effects of Synthetic Cannabinoid EAM-2201 on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

EAM-2201, a synthetic cannabinoid, is a potent agonist of the cannabinoid receptors that is widely abused as an illicit recreational drug in combination with other drugs. To evaluate the potential of EAM-2201 as a perpetrator of drug–drug interactions, the inhibitory effects of EAM-2201 on major dru...

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Udgivet i:Molecules
Main Authors: Kong, Tae Yeon, Kwon, Soon-Sang, Cheong, Jae Chul, Kim, Hee Seung, Kim, Jin Young, Lee, Hye Suk
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017357/
https://ncbi.nlm.nih.gov/pubmed/29659506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040920
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