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A Turn-on Fluorescence Sensor for Heparin Detection Based on a Release of Taiwan Cobra Cardiotoxin from a DNA Aptamer or Adenosine-Based Molecular Beacon

This study presents two sensitive fluorescent assays for sensing heparin on the basis of the electrostatic interaction between heparin and Naja naja atra cardiotoxin 3 (CTX3). Owing to CTX3-induced folded structure of an adenosine-based molecular beacon (MB) or a DNA aptamer against CTX3, a reductio...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Shi, Yi-Jun, Wang, Liang-Jun, Lee, Yuan-Chin, Huang, Chia-Hui, Hu, Wan-Ping, Chang, Long-Sen
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017339/
https://ncbi.nlm.nih.gov/pubmed/29463054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020460
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