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The Effects of Aronia melanocarpa ‘Viking’ Extracts in Attenuating RANKL-Induced Osteoclastic Differentiation by Inhibiting ROS Generation and c-FOS/NFATc1 Signaling

This study aimed to determine the anti-osteoclastogenic effects of extracts from Aronia melanocarpa ‘Viking’ (AM) and identify the underlying mechanisms in vitro. Reactive oxygen species (ROS) are signal mediators in osteoclast differentiation. AM extracts inhibited ROS production in RAW 264.7 cells...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ghosh, Mithun, Kim, In Sook, Lee, Young Min, Hong, Seong Min, Lee, Taek Hwan, Lim, Ji Hong, Debnath, Trishna, Lim, Beong Ou
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017336/
https://ncbi.nlm.nih.gov/pubmed/29518052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23030615
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