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Cell Penetrating Capacity and Internalization Mechanisms Used by the Synthetic Peptide CIGB-552 and Its Relationship with Tumor Cell Line Sensitivity

CIGB-552 is a twenty-amino-acid novel synthetic peptide that has proven to be effective in reducing tumor size and increasing lifespan in tumor-bearing mice. Such capability is conferred by its cell-penetrating peptide character, which allows it to enter cells and elicit a pro-apoptotic effect throu...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Astrada, Soledad, Fernández Massó, Julio Raúl, Vallespí, Maribel G., Bollati-Fogolín, Mariela
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017325/
https://ncbi.nlm.nih.gov/pubmed/29601540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040801
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