Spiroketones and a Biphenyl Analog from Stems and Leaves of Larrea nitida and Their Inhibitory Activity against IL-6 Production

Bioactivity-guided fractionation for the stems of leaves of Larrea nitida Cav., using interleukin-6 (IL-6) inhibitory assay in human mast cells (HMC-1), led to the isolation of three new compounds with an unprecedented skeleton in nature (1–3) and three known compounds (4–6). Their structures were e...

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Pubblicato in:Molecules
Autori principali: Ahn, Jongmin, Pei, Yihua, Chae, Hee-Sung, Kim, Seong-Hwan, Kim, Young-Mi, Choi, Young Hee, Lee, Joongku, Chang, Minsun, Song, Yun Seon, Rodriguez, Roberto, Oh, Dong-Chan, Kim, Jinwoong, Choi, Sangho, Joo, Sang Hoon, Chin, Young-Won
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017194/
https://ncbi.nlm.nih.gov/pubmed/29385086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020302
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