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Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets
Trisomy of chromosome 21 (TS21) is the most common autosomal aneuploidy compatible with postnatal survival with a prevalence of 1 in 700 newborns. Its phenotype is highly complex with constant features, such as mental retardation, dysmorphic traits and hypotonia, and variable features including hear...
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| Pubblicato in: | Mol Med |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016872/ https://ncbi.nlm.nih.gov/pubmed/30134785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0004-y |
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