Targeting DEC-205(−)DCIR2(+) dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis

BACKGROUND: Dendritic cells (DC) induce adaptive responses against foreign antigens, and play an essential role in maintaining peripheral tolerance to self-antigens. Therefore they are involved in preventing fatal autoimmunity. Selective delivery of antigens to immature DC via the endocytic DEC-205...

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Pubblicato in:Mol Med
Autori principali: Tabansky, Inna, Keskin, Derin B., Watts, Deepika, Petzold, Cathleen, Funaro, Michael, Sands, Warren, Wright, Paul, Yunis, Edmond J., Najjar, Souhel, Diamond, Betty, Cao, Yonghao, Mooney, David, Kretschmer, Karsten, Stern, Joel N. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016871/
https://ncbi.nlm.nih.gov/pubmed/30134798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0017-6
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