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Bidirectional transendothelial migration of monocytes across hepatic sinusoidal endothelium shapes monocyte differentiation and regulates the balance between immunity and tolerance in liver

BACKGROUND: Monocytes are versatile cells that can fulfil pro- and anti-inflammatory functions when recruited to the liver. Recruited monocytes differentiate into tissue macrophages and dendritic cells, which sample antigens and migrate to lymph nodes to elicit T-cell responses. The signals that det...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Zimmermann, Henning W, Bruns, Tony, Weston, Chris J, Curbishley, Stuart M, Liaskou, Evaggelia, Li, Ka-Kit, Resheq, Yazid J, Badenhorst, Paul W., Adams, David H
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016741/
https://ncbi.nlm.nih.gov/pubmed/26473398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28285
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