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Central IKK2 Inhibition Ameliorates Air Pollution-Mediated Hepatic Glucose and Lipid Metabolism Dysfunction in Mice With Type II Diabetes

Previous studies supported a role of hypothalamic inflammation in fine ambient particulate matter (PM(2.5)) exposure-mediated diabetes development. We therefore investigated the effects of PM(2.5) exposure on insulin resistance and the disorders of hepatic glucose and lipid metabolism via hypothalam...

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Foilsithe in:Toxicol Sci
Main Authors: Sun, Qing, Zhang, Guoqing, Chen, Rucheng, Li, Ran, Wang, Huanhuan, Jiang, Apei, Li, Zhenwei, Kong, Liya, Fonken, Laura K, Rajagopalan, Sanjay, Sun, Qinghua, Liu, Cuiqing
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016715/
https://ncbi.nlm.nih.gov/pubmed/29635361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy079
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