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Medication class enrichment analysis: a novel algorithm to analyze multiple pharmacologic exposures simultaneously using electronic health record data

OBJECTIVE: Observational studies analyzing multiple exposures simultaneously have been limited by difficulty distinguishing relevant results from chance associations due to poor specificity. Set-based methods have been successfully used in genomics to improve signal-to-noise ratio. We present and de...

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Podrobná bibliografie
Vydáno v:J Am Med Inform Assoc
Hlavní autoři: Vajravelu, Ravy K, Scott, Frank I, Mamtani, Ronac, Li, Hongzhe, Moore, Jason H, Lewis, James D
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016702/
https://ncbi.nlm.nih.gov/pubmed/29378062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jamia/ocx162
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