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Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism

The kynurenine pathway is the primary route for l-tryptophan degradation in mammals. Intermediates and side products of this pathway are involved in immune response and neurodegenerative diseases. This makes the study of enzymes, especially those from mammalian sources, of the kynurenine pathway wor...

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Pubblicato in:J Biol Chem
Autori principali: Davis, Ian, Yang, Yu, Wherritt, Daniel, Liu, Aimin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016481/
https://ncbi.nlm.nih.gov/pubmed/29703752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003320
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