Impact of the M184V Resistance Mutation on Virological Efficacy and Durability of Lamivudine-Based Dual Antiretroviral Regimens as Maintenance Therapy in Individuals With Suppressed HIV-1 RNA: A Cohort Study

BACKGROUND: Dual therapy (DT) with boosted protease inhibitors (bPIs) plus lamivudine has been shown to be superior to bPI monotherapy in virologically suppressed patients despite previous selection of the lamivudine resistance M184V mutation. We compared the virological efficacy of lamivudine-based...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Gagliardini, Roberta, Ciccullo, Arturo, Borghetti, Alberto, Maggiolo, Franco, Bartolozzi, Dario, Borghi, Vanni, Pecorari, Monica, Di Biagio, Antonio, Callegaro, Anna Paola, Bruzzone, Bianca, Saladini, Francesco, Paolucci, Stefania, Maserati, Renato, Zazzi, Maurizio, Di Giambenedetto, Simona, De Luca, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016422/
https://ncbi.nlm.nih.gov/pubmed/29977967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy113
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