Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile

Clostridium difficile is the major etiologic agent of antibiotic-associated intestinal disease. Pathogenesis of C. difficile is mainly attributed to the production and secretion of toxins A and B. Unlike most clostridial toxins, toxins A and B have no signal peptide, and they are therefore secreted...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Wydau-Dematteis, Sandra, El Meouche, Imane, Courtin, Pascal, Hamiot, Audrey, Lai-Kuen, René, Saubaméa, Bruno, Fenaille, François, Butel, Marie-José, Pons, Jean-Louis, Dupuy, Bruno, Chapot-Chartier, Marie-Pierre, Peltier, Johann
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016235/
https://ncbi.nlm.nih.gov/pubmed/29895635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00648-18
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