Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci

BACKGROUND: Eosinophilic esophagitis (EoE) is an esophageal inflammatory disease associated with atopic diseases. Thymic stromal lymphopoietin (TSLP) and calpain 14 (CAPN14) genetic variations contribute to EoE, but how this relates to atopy is unclear. OBJECTIVE: The purpose of this study was to ex...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Martin, Lisa J., He, Hua, Collins, Margaret H., Abonia, J. Pablo, Biagini Myers, Joceyln M., Eby, Michael, Johansson, Hanna, Kottyan, Leah C., Khurana Hershey, Gurjit K., Rothenberg, Marc E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016040/
https://ncbi.nlm.nih.gov/pubmed/29129581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.09.046
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