Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci

BACKGROUND: Eosinophilic esophagitis (EoE) is an esophageal inflammatory disease associated with atopic diseases. Thymic stromal lymphopoietin (TSLP) and calpain 14 (CAPN14) genetic variations contribute to EoE, but how this relates to atopy is unclear. OBJECTIVE: The purpose of this study was to ex...

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Dades bibliogràfiques
Publicat a:J Allergy Clin Immunol
Autors principals: Martin, Lisa J., He, Hua, Collins, Margaret H., Abonia, J. Pablo, Biagini Myers, Joceyln M., Eby, Michael, Johansson, Hanna, Kottyan, Leah C., Khurana Hershey, Gurjit K., Rothenberg, Marc E.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016040/
https://ncbi.nlm.nih.gov/pubmed/29129581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.09.046
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