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Subgroup identification in clinical trials: an overview of available methods and their implementations with R

Randomized controlled trials (RCTs) usually enroll heterogeneous study population, and thus it is interesting to identify subgroups of patients for whom the treatment may be beneficial or harmful. A variety of methods have been developed to do such kind of post hoc analyses. Conventional generalized...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Zhang, Zhongheng, Seibold, Heidi, Vettore, Mario V., Song, Woo-Jung, François, Vieille
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015941/
https://ncbi.nlm.nih.gov/pubmed/29955582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2018.03.07
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