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Subtype-specific cancer-associated fibroblasts contribute to the pathogenesis of uterine leiomyoma

Recent genomic studies have identified subtypes of uterine leiomyoma (LM) with distinctive genetic alterations. Here we report the elucidation of the biological characteristics of the two most prevalent LM subtypes, MED12 mutant (MED12-LM) and HMGA2-overexpressing (HMGA2-LM) LM. Since each tumor car...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Wu, Xin, Serna, Vanida A., Thomas, Justin, Qiang, Wenan, Blumenfeld, Michael L., Kurita, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015476/
https://ncbi.nlm.nih.gov/pubmed/29055020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1744
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