Rac1 Modulates Endothelial Function and Platelet Aggregation in Diabetes Mellitus

BACKGROUND: Vascular complications and abnormal platelet function contribute to morbidity and mortality in diabetes mellitus. We hypothesized that the Rho‐related GTPase protein, Rac1, can influence both endothelial and platelet function and might represent a potential novel therapeutic target in di...

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Bibliographic Details
Published in:J Am Heart Assoc
Main Authors: Schiattarella, Gabriele Giacomo, Carrizzo, Albino, Ilardi, Federica, Damato, Antonio, Ambrosio, Mariateresa, Madonna, Michele, Trimarco, Valentina, Marino, Marina, De Angelis, Elena, Settembrini, Silvio, Perrino, Cinzia, Trimarco, Bruno, Esposito, Giovanni, Vecchione, Carmine
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015399/
https://ncbi.nlm.nih.gov/pubmed/29626150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007322
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