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Characterization of a Di-leucine–based Signal in the Cytoplasmic Tail of the Nucleotide-pyrophosphatase NPP1 That Mediates Basolateral Targeting but not Endocytosis

Enzymes of the nucleotide pyrophosphatase/phosphodiesterase (NPPase) family are expressed at opposite surfaces in polarized epithelial cells. We investigated the targeting signal of NPP1, which is exclusively expressed at the basolateral surface. Full-length NPP1 and different constructs and mutants...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Bello, Valérie, Goding, James W., Greengrass, Vicki, Sali, Adnan, Dubljevic, Valentina, Lenoir, Christelle, Trugnan, Germain, Maurice, Michèle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598187/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.10.3004
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