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Bayesian Multi-Plate High-Throughput Screening of Compounds

High-throughput screening of compounds (chemicals) is an essential part of drug discovery, involving thousands to millions of compounds, with the purpose of identifying candidate hits. Most statistical tools, including the industry standard B-score method, work on individual compound plates and do n...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Shterev, Ivo D., Dunson, David B., Chan, Cliburn, Sempowski, Gregory D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015058/
https://ncbi.nlm.nih.gov/pubmed/29934615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27531-w
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