Nintedanib inhibits growth of human prostate carcinoma cells by modulating both cell cycle and angiogenesis regulators

Prostate cancer (PCa) is the most common malignancy and second leading cause of cancer-related deaths in American men. Proliferating cells have higher need for nutrients and oxygen, triggering angiogenesis that plays a critical role in tumor growth, progression and metastasis. Consequently, immense...

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Publicado no:Sci Rep
Main Authors: da Silva, Raquel Frenedoso, Dhar, Deepanshi, Raina, Komal, Kumar, Dileep, Kant, Rama, Cagnon, Valeria Helena Alves, Agarwal, Chapla, Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014981/
https://ncbi.nlm.nih.gov/pubmed/29934570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27831-1
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