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KRAS Activating Signaling Triggers Arteriovenous Malformations

The underlying genetic causes and altered signaling pathways of brain arteriovenous malformations remains unknown. A study published in The New England Journal of Medicine reported that KRAS somatic mutations (p.Gly12Val/Asp) were identified in brain arteriovenous malformations of human subjects and...

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Foilsithe in:Trends Biochem Sci
Main Authors: Cheng, Feixiong, Nussinov, Ruth
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014919/
https://ncbi.nlm.nih.gov/pubmed/29748115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.04.007
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