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Architecture of PRC2 holo complexes

Polycomb repressive complex 2 (PRC2) is a chief epigenetic regulator. Chen et al. describe the crystal structure of the heterotetrameric PRC2 holo complex that provides new mechanistic insights into subunits organization and PRC2 association with chromatin.

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Detalles Bibliográficos
Publicado en:Trends Biochem Sci
Main Authors: Vann, Kendra R., Kutateladze, Tatiana G.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014913/
https://ncbi.nlm.nih.gov/pubmed/29731341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.04.009
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